A04502

antibody from Boster Biological Technology

Targeting: KCNK1 DPK, K2p1.1, TWIK-1

Western blot (Data presented on provider website)

Antibody Data

Product number

A04502

Provider

Boster Biological Technology

Product name

Anti-KCNK1/Twik 1 Antibody

Antibody type

Polyclonal

Description

Polyclonal antibody for TWIK 1/KCNK1 detection. Host: Rabbit.Size: 100μl. Tested applications: WB. Reactive species: Human. TWIK 1/KCNK1 information: Molecular Weight: 38143 MW; Subcellular Localization: Cell membrane ; Multi-pass membrane protein . Recycling endosome . Cell junction, synapse . Cytoplasmic vesicle . Perikaryon . Cell projection, dendrite . Cell projection . Apical cell membrane ; Multi-pass membrane protein . The heterodimer with KCNK2 is detected at the astrocyte cell membrane. Not detected at the astrocyte cell membrane when KCNK2 is absent. Detected on neuronal cell bodies, and to a lesser degree on neuronal cell projections. Detected on hippocampus dentate gyrus granule cell bodies and to a lesser degree on proximal dendrites. Detected in synaptic membranes. Detected at the apical cell membrane in stria vascularis in the cochlea. Detected at the apical cell membrane of vestibular dark cells situated between the crista and the utricle in the inner ear. Detected at the apical cell membrane in kidney proximal tubule segment S1 and in subapical compartments in segments S1, S2 and S3. Predominantly in cytoplasmic structures in kidney distal convoluted tubules and collecting ducts (By similarity). Detected at the apical cell membrane of bronchial epithelial cells (PubMed:21964404); Tissue Specificity: Detected in bronchial epithelial cells (PubMed:21964404). Detected in heart left atrium and left ventricle (PubMed:17478540). Detected in cardiac myocytes (at protein level) (PubMed:21653227). Widely expressed with high levels in heart, brain and kidney, and lower levels in colon, ovary, placenta, lung and liver (PubMed:8605869, PubMed:9362344). Highly expressed in cerebellum, and detected at lower levels in amygdala, caudate nucleus, brain cortex, hippocampus, putamen, substantia nigra, thalamus, dorsal root ganglion, spinal cord, pituitary, heart, kidney, lung, placenta, pancreas, stomach, small intestine, uterus and prostate (PubMed:11165377). Detected in right and left heart ventricle and atrium, and in heart Purkinje fibers (PubMed:17478540). Detected in bronchial epithelial cells (PubMed:21964404).

Reactivity

Human, Rat

Host

Rabbit

Vial size

100μl

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Storage

Store at -20°C for one year, at 4°C for one month. We suggest the antibody be aliquoted into small vials and stored frozen at -20°C upon receiving. Avoid repeated freezing and thawing.