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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [2]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- GTX54857 - Provider product page
- Provider
- GeneTex
- Product name
- TrkB antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
Submitted references Ablation of ErbB4 in parvalbumin-positive interneurons inhibits adult hippocampal neurogenesis through down-regulating BDNF/TrkB expression.
BNN-20, a synthetic microneurotrophin, strongly protects dopaminergic neurons in the "weaver" mouse, a genetic model of dopamine-denervation, acting through the TrkB neurotrophin receptor.
Subchronic Arsenic Exposure Induces Anxiety-Like Behaviors in Normal Mice and Enhances Depression-Like Behaviors in the Chemically Induced Mouse Model of Depression.
Zhang H, He X, Mei Y, Ling Q
The Journal of comparative neurology 2018 Oct 15;526(15):2482-2492
The Journal of comparative neurology 2018 Oct 15;526(15):2482-2492
BNN-20, a synthetic microneurotrophin, strongly protects dopaminergic neurons in the "weaver" mouse, a genetic model of dopamine-denervation, acting through the TrkB neurotrophin receptor.
Botsakis K, Mourtzi T, Panagiotakopoulou V, Vreka M, Stathopoulos GT, Pediaditakis I, Charalampopoulos I, Gravanis A, Delis F, Antoniou K, Zisimopoulos D, Georgiou CD, Panagopoulos NT, Matsokis N, Angelatou F
Neuropharmacology 2017 Jul 15;121:140-157
Neuropharmacology 2017 Jul 15;121:140-157
Subchronic Arsenic Exposure Induces Anxiety-Like Behaviors in Normal Mice and Enhances Depression-Like Behaviors in the Chemically Induced Mouse Model of Depression.
Chang CY, Guo HR, Tsai WC, Yang KL, Lin LC, Cheng TJ, Chuu JJ
BioMed research international 2015;2015:159015
BioMed research international 2015;2015:159015
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- WB analysis of mouse brain lysates using TrkB antibody at a dilution of 1:200 in the (1) absence or (2) presence of blocking peptide.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- WB analysis of rat brain membranes (lanes 1 and 3) and HEK-TrkB transfected cell lysates (lanes 2 and 4) using TrkB antibody at a dilution of 1:200 in the absence (lens 1 and 2) or presence (lens 3 and 4) of blocking peptide.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- ICC/IF analysis of PC12 cells using TrkB antibody at a dilution of 1:50 (red). (B) Live view of the cells. (C) Merge of the two images.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- IHC-Fr analysis of rat DRG using TrkB antibody at a dilution of 1:100 (red) and Hoechst 33342 (blue).
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- FACS analysis of HL-60 cells using TrkB antibody (green) and an isotype control (black).
