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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- PAB18081 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB18081, RRID:AB_10719062
- Product name
- ALK polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of ALK.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling.
Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3.
Prognostic significance of CD56 expression for ALK-positive and ALK-negative anaplastic large-cell lymphoma of T/null cell phenotype.
Lymphomas expressing ALK fusion protein(s) other than NPM-ALK.
Staber PB, Vesely P, Haq N, Ott RG, Funato K, Bambach I, Fuchs C, Schauer S, Linkesch W, Hrzenjak A, Dirks WG, Sexl V, Bergler H, Kadin ME, Sternberg DW, Kenner L, Hoefler G
Blood 2007 Nov 1;110(9):3374-83
Blood 2007 Nov 1;110(9):3374-83
Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3.
Kasprzycka M, Marzec M, Liu X, Zhang Q, Wasik MA
Proceedings of the National Academy of Sciences of the United States of America 2006 Jun 27;103(26):9964-9
Proceedings of the National Academy of Sciences of the United States of America 2006 Jun 27;103(26):9964-9
Prognostic significance of CD56 expression for ALK-positive and ALK-negative anaplastic large-cell lymphoma of T/null cell phenotype.
Suzuki R, Kagami Y, Takeuchi K, Kami M, Okamoto M, Ichinohasama R, Mori N, Kojima M, Yoshino T, Yamabe H, Shiota M, Mori S, Ogura M, Hamajima N, Seto M, Suchi T, Morishima Y, Nakamura S
Blood 2000 Nov 1;96(9):2993-3000
Blood 2000 Nov 1;96(9):2993-3000
Lymphomas expressing ALK fusion protein(s) other than NPM-ALK.
Falini B, Pulford K, Pucciarini A, Carbone A, De Wolf-Peeters C, Cordell J, Fizzotti M, Santucci A, Pelicci PG, Pileri S, Campo E, Ott G, Delsol G, Mason DY
Blood 1999 Nov 15;94(10):3509-15
Blood 1999 Nov 15;94(10):3509-15
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of HeLa cells, using ALK polyclonal antibody (Cat # PAB18081).Peptide "+" means "with peptide blocking".
- Validation comment
- Immunofluorescence
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of paraffin-embedded human brain tissue using ALK polyclonal antibody (Cat # PAB18081).Peptide "+" means "with peptide blocking".
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
