FNab00310

antibody from FineTest Biotech

Targeting: ALK CD246

Western blot

ELISA

Immunohistochemistry

Antibody data

Submit

Validation data

Product number: FNab00310 - Provider product page
Provider: FineTest Biotech
Product name: ALK,CD246 antibody
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: ALK, also named as CD246, is a receptor tyrosine kinase(RTK) that belongs to the protein kinase superfamily. ALK is usually found in the nervous system and appears to play an important role in the normal development and function of the nervous system. ALK was originally identified as part of the NPM(Nucleophosmin)-ALK oncogenic fusion protein, resulting from the(2;5)(p23;q35) translocation that is frequently associated with anaplastic large-cell lymphoma(ALCL). The EML4(echinoderm microtubule-associated protein-like 4)-ALK fusion protein have been described in non-small-cell lung cancer(NSCLC), this transforming fusion kinase is a promising candidate for a therapeutic target as well as for a diagnostic molecular marker in NSCLC(PMID: 17625570).
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: anaplastic lymphoma receptor tyrosi ne kinase
Epitope: IgG2a
Isotype: IgG
Antibody clone number: 2B10
Vial size: 100¦Ìg
Concentration: Protein A+G purification
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ALK protein structure - FNab00310 shown in red.