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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB2176 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2176, RRID:AB_1579192
- Product name
- PRMT6 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PRMT6.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad.
The novel human protein arginine N-methyltransferase PRMT6 is a nuclear enzyme displaying unique substrate specificity.
Prmt5, which forms distinct homo-oligomers, is a member of the protein-arginine methyltransferase family.
Pal S, Yun R, Datta A, Lacomis L, Erdjument-Bromage H, Kumar J, Tempst P, Sif S
Molecular and cellular biology 2003 Nov;23(21):7475-87
Molecular and cellular biology 2003 Nov;23(21):7475-87
The novel human protein arginine N-methyltransferase PRMT6 is a nuclear enzyme displaying unique substrate specificity.
Frankel A, Yadav N, Lee J, Branscombe TL, Clarke S, Bedford MT
The Journal of biological chemistry 2002 Feb 1;277(5):3537-43
The Journal of biological chemistry 2002 Feb 1;277(5):3537-43
Prmt5, which forms distinct homo-oligomers, is a member of the protein-arginine methyltransferase family.
Rho J, Choi S, Seong YR, Cho WK, Kim SH, Im DS
The Journal of biological chemistry 2001 Apr 6;276(14):11393-401
The Journal of biological chemistry 2001 Apr 6;276(14):11393-401
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The PRMT6 polyclonal antibody (Cat # PAB2176) was used to detect human PRMT6 protein in human brain extract in a Western blot analysis.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
