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LearnPAB12394
antibody from Abnova Corporation
Targeting: LRRK2
DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [2]
- Immunocytochemistry [1]
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- Product number
- PAB12394 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12394, RRID:AB_10553053
- Product name
- LRRK2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of LRRK2.
- Storage
- Store at 4°C. Do not freeze.
Submitted references A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease.
LRRK2 expression in normal and pathologic human brain and in human cell lines.
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease.
Melrose HL, Kent CB, Taylor JP, Dachsel JC, Hinkle KM, Lincoln SJ, Mok SS, Culvenor JG, Masters CL, Tyndall GM, Bass DI, Ahmed Z, Andorfer CA, Ross OA, Wszolek ZK, Delldonne A, Dickson DW, Farrer MJ
Neuroscience 2007 Jul 29;147(4):1047-58
Neuroscience 2007 Jul 29;147(4):1047-58
LRRK2 expression in normal and pathologic human brain and in human cell lines.
Miklossy J, Arai T, Guo JP, Klegeris A, Yu S, McGeer EG, McGeer PL
Journal of neuropathology and experimental neurology 2006 Oct;65(10):953-63
Journal of neuropathology and experimental neurology 2006 Oct;65(10):953-63
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.
Zimprich A, Biskup S, Leitner P, Lichtner P, Farrer M, Lincoln S, Kachergus J, Hulihan M, Uitti RJ, Calne DB, Stoessl AJ, Pfeiffer RF, Patenge N, Carbajal IC, Vieregge P, Asmus F, Müller-Myhsok B, Dickson DW, Meitinger T, Strom TM, Wszolek ZK, Gasser T
Neuron 2004 Nov 18;44(4):601-7
Neuron 2004 Nov 18;44(4):601-7
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease.
Paisán-Ruíz C, Jain S, Evans EW, Gilks WP, Simón J, van der Brug M, López de Munain A, Aparicio S, Gil AM, Khan N, Johnson J, Martinez JR, Nicholl D, Carrera IM, Pena AS, de Silva R, Lees A, Martí-Massó JF, Pérez-Tur J, Wood NW, Singleton AB
Neuron 2004 Nov 18;44(4):595-600
Neuron 2004 Nov 18;44(4):595-600
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of LRRK2 in HeLa whole cell lysate (RIPA) using LRRK2 polyclonal antibody (Cat # PAB12394) at 1 : 5,000 dilution.
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of LRRK2 in 50 ug of crude bovine brain membrane using LRRK2 polyclonal antibody (Cat # PAB12394).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunofluorescent CAD cells transfected with human wild-type LRRK2 (1 : 2000) using LRRK2 polyclonal antibody (Cat # PAB12394).
- Validation comment
- Immunofluorescence
