BS4460

antibody from Bioworld Technology, Inc

Targeting: KSR1 KSR, RSU2

Immunohistochemistry

Antibody data

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Validation data

Product number: BS4460 - Provider product page
Provider: Bioworld Technology, Inc
Product name: Ksr 1 (phospho S392) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic phosphopeptide derived from human Ksr-1 around the phosphorylation site of Serine 392.
Description: Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk) and Raf-1. Raf-1 has intrinsic kinase activity towards serine/threonine residues and is widely expressed in many tissue types and cell lines. Raf-1 activation is dependent on the small molecular weight GTPase Ras, but the means by which this activation occurs is poorly understood. Two proteins putatively involved in this process are Ksr-1 and Tak1. Ksr-1 (kinase suppressor of Ras) is a novel Raf-related protein kinase whose function is required for Ras signal transduction. Whether Ksr-1 lies directly downstream of Ras or acts in a parallel pathway is not yet known. Tak1 (TGFb-activated kinase) has been shown to participate in the activation of the MAP kinase family in response to TGFb stimulation.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

KSR1 protein structure - BS4460 shown in red.