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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN499851 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A) antibody
- Antibody type
- Polyclonal
- Antigen
- Fn14 antibody was raised against a human IgG1 Fc-tagged Fn14 protein. (AP30344°CP-N)
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C.
Submitted references Fibroblast growth factor-inducible 14 mediates multiple pathways of TWEAK-induced cell death.
The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation.
The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas.
TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis.
Nakayama M, Ishidoh K, Kojima Y, Harada N, Kominami E, Okumura K, Yagita H
Journal of immunology (Baltimore, Md. : 1950) 2003 Jan 1;170(1):341-8
Journal of immunology (Baltimore, Md. : 1950) 2003 Jan 1;170(1):341-8
The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation.
Brown SA, Richards CM, Hanscom HN, Feng SL, Winkles JA
The Biochemical journal 2003 Apr 15;371(Pt 2):395-403
The Biochemical journal 2003 Apr 15;371(Pt 2):395-403
The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas.
Feng SL, Guo Y, Factor VM, Thorgeirsson SS, Bell DW, Testa JR, Peifley KA, Winkles JA
The American journal of pathology 2000 Apr;156(4):1253-61
The American journal of pathology 2000 Apr;156(4):1253-61
TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis.
Chicheportiche Y, Bourdon PR, Xu H, Hsu YM, Scott H, Hession C, Garcia I, Browning JL
The Journal of biological chemistry 1997 Dec 19;272(51):32401-10
The Journal of biological chemistry 1997 Dec 19;272(51):32401-10
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of Fn14 in HepG2 cells with AP30344PU-N Fn14 antibody at (A) 2 and (B) 4 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of Fn14 in human liver tissue with AP30344PU-N Fn14 antibody at 2.5 ?g/ml.
