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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Product number
- MAB6941 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal GITR Ligand/TNFSF18 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects human GITR Ligand/TNFSF18 in direct ELISAs.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 500 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Generation and preclinical characterization of a Fc-optimized GITR-Ig fusion protein for induction of NK cell reactivity against leukemia.
Neutralization of tumor-derived soluble glucocorticoid-induced TNFR-related protein ligand increases NK cell anti-tumor reactivity.
Cancer immunoediting by GITR (glucocorticoid-induced TNF-related protein) ligand in humans: NK cell/tumor cell interactions.
Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL).
Staphylococcal enterotoxin B inhibits regulatory T cells by inducing glucocorticoid-induced TNF receptor-related protein ligand on monocytes.
Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function.
Schmiedel BJ, Werner A, Steinbacher J, Nuebling T, Buechele C, Grosse-Hovest L, Salih HR
Molecular therapy : the journal of the American Society of Gene Therapy 2013 Apr;21(4):877-86
Molecular therapy : the journal of the American Society of Gene Therapy 2013 Apr;21(4):877-86
Neutralization of tumor-derived soluble glucocorticoid-induced TNFR-related protein ligand increases NK cell anti-tumor reactivity.
Baltz KM, Krusch M, Baessler T, Schmiedel BJ, Bringmann A, Brossart P, Salih HR
Blood 2008 Nov 1;112(9):3735-43
Blood 2008 Nov 1;112(9):3735-43
Cancer immunoediting by GITR (glucocorticoid-induced TNF-related protein) ligand in humans: NK cell/tumor cell interactions.
Baltz KM, Krusch M, Bringmann A, Brossart P, Mayer F, Kloss M, Baessler T, Kumbier I, Peterfi A, Kupka S, Kroeber S, Menzel D, Radsak MP, Rammensee HG, Salih HR
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 Aug;21(10):2442-54
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 Aug;21(10):2442-54
Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL).
Hanabuchi S, Watanabe N, Wang YH, Wang YH, Ito T, Shaw J, Cao W, Qin FX, Liu YJ
Blood 2006 May 1;107(9):3617-23
Blood 2006 May 1;107(9):3617-23
Staphylococcal enterotoxin B inhibits regulatory T cells by inducing glucocorticoid-induced TNF receptor-related protein ligand on monocytes.
Cardona ID, Goleva E, Ou LS, Leung DY
The Journal of allergy and clinical immunology 2006 Mar;117(3):688-95
The Journal of allergy and clinical immunology 2006 Mar;117(3):688-95
Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function.
Godfrey WR, Spoden DJ, Ge YG, Baker SR, Liu B, Levine BL, June CH, Blazar BR, Porter SB
Blood 2005 Jan 15;105(2):750-8
Blood 2005 Jan 15;105(2):750-8
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