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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Product number
- MAB6942-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Human GITR Ligand/TNFSF18 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human GITR Ligand/TNFSF18 in ELISAs. In sandwich immunoassays, no cross-reactivity or interference with recombinant human (rh) APRIL, rhLIGHT, rhTNF-alpha , or rhVEGI is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
Q9UNG2- Isotype
- IgG
- Antibody clone number
- 109114
- Vial size
- 100 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells.
Cancer immunoediting by GITR (glucocorticoid-induced TNF-related protein) ligand in humans: NK cell/tumor cell interactions.
Glucocorticoid-induced tumour necrosis factor receptor (GITR) and its ligand (GITRL) in atopic dermatitis.
Expression of GITR ligand abrogates immunosuppressive function of ocular tissue and differentially modulates inflammatory cytokines and chemokines.
Tuyaerts S, Van Meirvenne S, Bonehill A, Heirman C, Corthals J, Waldmann H, Breckpot K, Thielemans K, Aerts JL
Journal of leukocyte biology 2007 Jul;82(1):93-105
Journal of leukocyte biology 2007 Jul;82(1):93-105
Cancer immunoediting by GITR (glucocorticoid-induced TNF-related protein) ligand in humans: NK cell/tumor cell interactions.
Baltz KM, Krusch M, Bringmann A, Brossart P, Mayer F, Kloss M, Baessler T, Kumbier I, Peterfi A, Kupka S, Kroeber S, Menzel D, Radsak MP, Rammensee HG, Salih HR
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 Aug;21(10):2442-54
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007 Aug;21(10):2442-54
Glucocorticoid-induced tumour necrosis factor receptor (GITR) and its ligand (GITRL) in atopic dermatitis.
Baumgartner-Nielsen J, Vestergaard C, Thestrup-Pedersen K, Deleuran M, Deleuran B
Acta dermato-venereologica 2006;86(5):393-8
Acta dermato-venereologica 2006;86(5):393-8
Expression of GITR ligand abrogates immunosuppressive function of ocular tissue and differentially modulates inflammatory cytokines and chemokines.
Mahesh SP, Li Z, Liu B, Fariss RN, Nussenblatt RB
European journal of immunology 2006 Aug;36(8):2128-38
European journal of immunology 2006 Aug;36(8):2128-38
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