FNab09530

antibody from FineTest Biotech
Targeting: WTAP KIAA0105, MGC3925, Mum2
Provider product page for FNab09530
Western blot
ELISA
Immunohistochemistry

Antibody data

Product number
FNab09530 - Provider product page
Provider
FineTest Biotech
Product name
WTAP antibody
Antibody type
Monoclonal
Antigen
Recombinant protein fragment
Description
Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine(m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle(PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator(PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability(PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes(PubMed:17095724).
Reactivity
Human, Mouse, Rat
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
Wilms tumor 1 associated protein
Epitope
IgG1
Isotype
IgG
Antibody clone number
9D4
Vial size
100¦Ìg
Concentration
Protein A+G purification
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
WTAP protein structure - FNab09530 shown in red.