CABT-B8401

antibody from Creative Diagnostics

Targeting: TNFRSF18 AITR, CD357, GITR

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Chromatin Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

CABT-B8401

Provider

Creative Diagnostics

Product name

Anti-TNFRSF18 (aa26-162) monoclonal antibody, clone VNBC314

Antibody type

Monoclonal

Description

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

VNBC314

Vial size

100 _l

Concentration

0.5~1.0 mg/ml (Lot Dependent)