Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- AF4414 - Provider product page
- Provider
- R&D Systems
- Product name
- Human Neuronal Pentraxin R/NPTXR Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human Neuronal Pentraxin R/NPTXR in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) NPTX2 and rhNPTX1 is observed.
- Reactivity
- Human
- Host
- Sheep
- Conjugate
- Unconjugated
- Antigen sequence
O95502
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references NPTX2 and cognitive dysfunction in Alzheimer's Disease.
Presynaptic Neuronal Pentraxin Receptor Organizes Excitatory and Inhibitory Synapses.
Neuronal pentraxin 2 supports clear cell renal cell carcinoma by activating the AMPA-selective glutamate receptor-4.
Xiao MF, Xu D, Craig MT, Pelkey KA, Chien CC, Shi Y, Zhang J, Resnick S, Pletnikova O, Salmon D, Brewer J, Edland S, Wegiel J, Tycko B, Savonenko A, Reeves RH, Troncoso JC, McBain CJ, Galasko D, Worley PF
eLife 2017 Mar 23;6
eLife 2017 Mar 23;6
Presynaptic Neuronal Pentraxin Receptor Organizes Excitatory and Inhibitory Synapses.
Lee SJ, Wei M, Zhang C, Maxeiner S, Pak C, Calado Botelho S, Trotter J, Sterky FH, Südhof TC
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Feb 1;37(5):1062-1080
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017 Feb 1;37(5):1062-1080
Neuronal pentraxin 2 supports clear cell renal cell carcinoma by activating the AMPA-selective glutamate receptor-4.
von Roemeling CA, Radisky DC, Marlow LA, Cooper SJ, Grebe SK, Anastasiadis PZ, Tun HW, Copland JA
Cancer research 2014 Sep 1;74(17):4796-810
Cancer research 2014 Sep 1;74(17):4796-810
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