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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN500724 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Sirtuin 2 (SIRT2) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- SIRT2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of the Human SIRT2 (AP30785CP-N).
- Description
- Peptide Affinity Chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C.
Submitted references The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation.
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease.
Sirtuin functions in health and disease.
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity.
Inoue T, Hiratsuka M, Osaki M, Oshimura M
Cell cycle (Georgetown, Tex.) 2007 May 2;6(9):1011-8
Cell cycle (Georgetown, Tex.) 2007 May 2;6(9):1011-8
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease.
Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC, McLean PJ, Young AB, Abagyan R, Feany MB, Hyman BT, Kazantsev AG
Science (New York, N.Y.) 2007 Jul 27;317(5837):516-9
Science (New York, N.Y.) 2007 Jul 27;317(5837):516-9
Sirtuin functions in health and disease.
Yamamoto H, Schoonjans K, Auwerx J
Molecular endocrinology (Baltimore, Md.) 2007 Aug;21(8):1745-55
Molecular endocrinology (Baltimore, Md.) 2007 Aug;21(8):1745-55
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.
North BJ, Marshall BL, Borra MT, Denu JM, Verdin E
Molecular cell 2003 Feb;11(2):437-44
Molecular cell 2003 Feb;11(2):437-44
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity.
Frye RA
Biochemical and biophysical research communications 1999 Jun 24;260(1):273-9
Biochemical and biophysical research communications 1999 Jun 24;260(1):273-9
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of SIRT2 in Mouse brain lysate with AP30785PU-N SIRT2 antibody at (A) 1 and (B) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human brain tissue using AP30785PU-N SIRT2 antibody at 2.5 ?g/ml.
