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- References [4]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN500726 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Sirtuin 2 (SIRT2) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- SIRT2 antibody was raised against a 17 amino acid peptide near the amino terminus of the human SIRT2.
- Description
- Peptide affinity chromtography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8°C for up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation.
Sirtuin functions in health and disease.
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity.
Inoue T, Hiratsuka M, Osaki M, Oshimura M
Cell cycle (Georgetown, Tex.) 2007 May 2;6(9):1011-8
Cell cycle (Georgetown, Tex.) 2007 May 2;6(9):1011-8
Sirtuin functions in health and disease.
Yamamoto H, Schoonjans K, Auwerx J
Molecular endocrinology (Baltimore, Md.) 2007 Aug;21(8):1745-55
Molecular endocrinology (Baltimore, Md.) 2007 Aug;21(8):1745-55
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.
North BJ, Marshall BL, Borra MT, Denu JM, Verdin E
Molecular cell 2003 Feb;11(2):437-44
Molecular cell 2003 Feb;11(2):437-44
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity.
Frye RA
Biochemical and biophysical research communications 1999 Jun 24;260(1):273-9
Biochemical and biophysical research communications 1999 Jun 24;260(1):273-9
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of SIRT2 in human brain lysate with AP30786PU-N at (A) 2.5 and (B) 5 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human brain tissue using AP30786PU-N at 2.5 ?g/ml.
