Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- 22515-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- EAAT2 antibody
- Antibody type
- Polyclonal
- Description
- EAAT2 antibody (Cat. #22515-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Photobiomodulation Therapy Ameliorates Glutamatergic Dysfunction in Mice with Chronic Unpredictable Mild Stress-Induced Depression.
Quantitative proteomic analysis of cortex in the depressive-like behavior of rats induced by the simulated complex space environment.
Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity.
RAGE Signaling pathway in hippocampus dentate gyrus involved in GLT-1 decrease induced by chronic unpredictable stress in rats.
Functional validation of a human GLUD2 variant in a murine model of Parkinson's disease.
Aucubin Alleviates Seizures Activity in Li-Pilocarpine-Induced Epileptic Mice: Involvement of Inhibition of Neuroinflammation and Regulation of Neurotransmission.
Ginsenoside Rb1 prevents MPTP-induced changes in hippocampal memory via regulation of the α-synuclein/PSD-95 pathway.
HIV and drug abuse mediate astrocyte senescence in a β-catenin-dependent manner leading to neuronal toxicity.
Baicalin protects neonatal rat brains against hypoxic-ischemic injury by upregulating glutamate transporter 1 via the phosphoinositide 3-kinase/protein kinase B signaling pathway.
Zhang D, Shen Q, Wu X, Xing D
Oxidative medicine and cellular longevity 2021;2021:6678276
Oxidative medicine and cellular longevity 2021;2021:6678276
Quantitative proteomic analysis of cortex in the depressive-like behavior of rats induced by the simulated complex space environment.
Min R, Chen Z, Wang Y, Deng Z, Zhang Y, Deng Y
Journal of proteomics 2021 Apr 15;237:104144
Journal of proteomics 2021 Apr 15;237:104144
Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity.
Sha L, Chen T, Deng Y, Du T, Ma K, Zhu W, Shen Y, Xu Q
Theranostics 2020;10(18):8415-8429
Theranostics 2020;10(18):8415-8429
RAGE Signaling pathway in hippocampus dentate gyrus involved in GLT-1 decrease induced by chronic unpredictable stress in rats.
Yang F, Wang H, Chen H, Ran D, Tang Q, Weng P, Sun Y, Jiang W
Brain research bulletin 2020 Oct;163:49-56
Brain research bulletin 2020 Oct;163:49-56
Functional validation of a human GLUD2 variant in a murine model of Parkinson's disease.
Zhang W, Gong J, Ding L, Zhang Z, Pan X, Chen X, Guo W, Zhang X, Yang X, Peng G, Lin Y, Gao F, Li Y, Zhu X, Xuan A, Wang S, Sun X, Zhang Y, Xu P
Cell death & disease 2020 Oct 22;11(10):897
Cell death & disease 2020 Oct 22;11(10):897
Aucubin Alleviates Seizures Activity in Li-Pilocarpine-Induced Epileptic Mice: Involvement of Inhibition of Neuroinflammation and Regulation of Neurotransmission.
Chen S, Zeng X, Zong W, Wang X, Chen L, Zhou L, Li C, Huang Q, Huang X, Zeng G, Hu K, Ouyang DS
Neurochemical research 2019 Feb;44(2):472-484
Neurochemical research 2019 Feb;44(2):472-484
Ginsenoside Rb1 prevents MPTP-induced changes in hippocampal memory via regulation of the α-synuclein/PSD-95 pathway.
Qu S, Meng X, Liu Y, Zhang X, Zhang Y
Aging 2019 Apr 4;11(7):1934-1964
Aging 2019 Apr 4;11(7):1934-1964
HIV and drug abuse mediate astrocyte senescence in a β-catenin-dependent manner leading to neuronal toxicity.
Yu C, Narasipura SD, Richards MH, Hu XT, Yamamoto B, Al-Harthi L
Aging cell 2017 Oct;16(5):956-965
Aging cell 2017 Oct;16(5):956-965
Baicalin protects neonatal rat brains against hypoxic-ischemic injury by upregulating glutamate transporter 1 via the phosphoinositide 3-kinase/protein kinase B signaling pathway.
Zhou ZQ, Li YL, Ao ZB, Wen ZL, Chen QW, Huang ZG, Xiao B, Yan XH
Neural regeneration research 2017 Oct;12(10):1625-1631
Neural regeneration research 2017 Oct;12(10):1625-1631
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The EAAT2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human EAAT2. This antibody recognizes human, mouse, rat antigen. The EAAT2 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.