BS3438

antibody from Bioworld Technology, Inc
Targeting: ANXA1 ANX1, LPC1
Provider product page for BS3438
Western blot
Immunohistochemistry

Antibody data

Product number
BS3438 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS3438, RRID:AB_1662119
Product name
Annexin I (N146) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 111-160 of Human Annexin I.
Description
The annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner and a unique amino terminal region which may confer binding specificity. The interaction between these proteins and biological membranes have led to the hypothesis that they are involved in cellular trafficking processes such as endocytosis, exocytosis and cellular adhesion. Annexin I, alternatively referred to as lipocortin, has been implicated as a mediator of the anti-inflammatory response produced by glucocorticoids and as an inhibitor of cPLA2, a potent mediator of inflammation. Annexin II, also called p36, has been shown to exist as a monomer or a heterotetramer, complexed with the S-100-related protein p11. This complex is termed calpactin I. In the tetrameric form, Annexin II is an efficient substrate of the PKC family and Src pp60.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ANXA1 protein structure - BS3438 shown in red.