BS5660

antibody from Bioworld Technology, Inc
Targeting: CGREF1 CGR11
Provider product page for BS5660
Western blot
Immunohistochemistry

Antibody data

Product number
BS5660 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CGREF1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to the 256-301 of Human CGREF1.
Description
CGREF1 (cell growth regulator with EF-hand domain 1), also known as CGR11, is a 301 amino acid secreted protein that contains two highly conserved calcium binding EF-hand domains, which are required for mediating cell-cell adhesion. Induced by p53, CGREF1 is able to inhibit cell growth in various cell lines. CGREF1 is encoded by a gene located on human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstr?m syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CGREF1 protein structure - BS5660 shown in red.