Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-Z318R - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Rabbit Anti-Human CLN8 Polyclonal Antibody
- Antibody type
- Polyclonal
- Description
- CLN8 recruits lysosomal soluble proteins in the endoplasmic reticulum (ER), delivers them to the Golgi apparatus via COPII-coated vesicles, and recycles back to the ER via COPI-coated vesicles. CLN8 interacts with the lysosomal soluble proteins through its large luminal loop. The export signal of CLN8 is localized in its cytosolic C-terminus. CLN8 deficiency results in depletion of enzymes at the lysosome. It can play a role in cell proliferation during neuronal differentiation and in protection against cell death.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Concentration
- Lot specific
- Storage
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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