BS8931

antibody from Bioworld Technology, Inc

Targeting: OSGEP GCPL1, KAE1, OSGEP1, PRSMG1, TCS3

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS8931

Provider

Bioworld Technology, Inc

Product name

OSGEP polyclonal antibody

Antibody type

Polyclonal

Antigen

Probable tRNA N6-adenosine threonylcarbamoyltransferaseUniRule annotation; N6-L-threonylcarbamoyladenine synthase; t(6)A synthase; O-sialoglycoprotein endopeptidaseUniRule annotation; hOSGEP; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEPUniRule annotation; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPUniRule annotation; OSGEP; GCPL1

Description

Osgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that is a member of the peptidase M22 family. Osgep specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but it does not cleave desialylated glycoproteins, unglycosylated proteins or glycoproteins that are only N-glycosylated. Though ubiquitously expressed at low levels, highest levels of Osgep are found in liver, skeletal muscle and kidney. OSGEPL1, also known as Qri7, is a 414 amino acid protein that belongs to the KAE1/YgjD family and exists as three alternatively spliced isoforms. In tRNAs that have codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.