BS4208

antibody from Bioworld Technology, Inc
Targeting: WNK1 HSAN2, HSN2, PPP1R167, PRKWNK1
Provider product page for BS4208
Western blot
Immunohistochemistry

Antibody data

Product number
BS4208 - Provider product page
Provider
Bioworld Technology, Inc
Product name
WNK1 (phospho T60) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human WNK1 around the phosphorylation site of Threonine 60.
Description
WNK1 (WNK lysine deficient protein kinase 1), also known as KDP (kinase deficient protein), PSK, erythrocyte 65 kDa protein (p65), HSN2, HSAN2 or PRKWNK1, is a 2,382 amino acid cytoplasmic protein that participates in cell signaling, proliferation and survival, and regulates electrolyte homeostasis. WNK1 belongs to the Ser/Thr protein kinase family of the protein kinase superfamily, and contains one protein kinase domain. Existing as five alternatively spliced isoforms, WNK1 is widely expressed but is found at highest levels in skeletal muscke, heart, testis and kidney. The gene that encodes WNK1 maps to human chromosome 12p13.33, and when defective, is the cause of an an autosomal dominant disease known as pseudohypoaldosteronism type II (PHAII), as well as a hereditary sensory and autonomic neuropathy designated hereditary sensory and autonomic neuropathy type 2A (HSAN2A).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
WNK1 protein structure - BS4208 shown in red.