ABIN953644

antibody from antibodies-online

Targeting: NEIL2 FLJ31644, MGC2832, MGC4505, NEH2

Western blot (Recommended by provider)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN953644

Provider

antibodies-online

Product name

anti-Nei Endonuclease VIII-Like 2 (E. Coli) (NEIL2) (AA 66-96), (N-Term) antibody

Antibody type

Polyclonal

Description

Protein A column, followed by peptide affinity purification

Reactivity

Human

Host

Rabbit

Epitope

N-Term, AA 66-96

Vial size

0.4 mL

Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Inactivation of NEIL2 DNA glycosylase by pyridoxal phosphate reveals a loop important for substrate binding.

Grin IR, Rieger RA, Zharkov DO
Biochemical and biophysical research communications 2010 Mar 26;394(1):100-5

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Variation within DNA repair pathway genes and risk of multiple sclerosis.

Briggs FB, Goldstein BA, McCauley JL, Zuvich RL, De Jager PL, Rioux JD, Ivinson AJ, Compston A, Hafler DA, Hauser SL, Oksenberg JR, Sawcer SJ, Pericak-Vance MA, Haines JL, Barcellos LF, International Multiple Sclerosis Genetics Consortium.
American journal of epidemiology 2010 Jul 15;172(2):217-24

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Single nucleotide polymorphisms 5' upstream the coding region of the NEIL2 gene influence gene transcription levels and alter levels of genetic damage.

Kinslow CJ, El-Zein RA, Hill CE, Wickliffe JK, Abdel-Rahman SZ
Genes, chromosomes & cancer 2008 Nov;47(11):923-32

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Functional variants of the NEIL1 and NEIL2 genes and risk and progression of squamous cell carcinoma of the oral cavity and oropharynx.

Zhai X, Zhao H, Liu Z, Wang LE, El-Naggar AK, Sturgis EM, Wei Q
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Jul 1;14(13):4345-52

Immunohistochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

IHC