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Protein structure
VCP
Valosin containing proteinCDC48, IBMPFD, p97, TERA
This gene encodes a member of the AAA ATPase family of proteins. The encoded protein plays a role in protein degradation, intracellular membrane fusion, DNA repair and replication, regulation of the cell cycle, and activation of the NF-kappa B pathway. This protein forms a homohexameric complex that interacts with a variety of cofactors and extracts ubiquitinated proteins from lipid membranes or protein complexes. Mutations in this gene cause IBMPFD (inclusion body myopathy with paget disease of bone and frontotemporal dementia), ALS (amyotrophic lateral sclerosis) and Charcot-Marie-Tooth disease in human patients. [provided by RefSeq, Aug 2017]
Top validated antibodies |
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| Proteintech Group |  10736-1-AP |
14 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | MA3-004 |
34 references | Monoclonal |
WB
ICC
IHC
OA
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| GeneTex | GTX101089 |
6 references | Polyclonal |
WB
ICC
IP
IHC
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| Novus Biologicals | NB120-11433 |
3 references | Monoclonal |
WB
ICC
IP
IHC
FC
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| antibodies-online | ABIN151101 |
4 references | Polyclonal |
WB
ICC
IP
IHC
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