BS6621

antibody from Bioworld Technology, Inc

Targeting: HFE HFE1, HLA-H

Immunocytochemistry

Immunohistochemistry

Antibody data

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Validation data

Product number: BS6621 - Provider product page
Provider: Bioworld Technology, Inc
Product name: HFE polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human HFE.
Description: The HFE protein, which is defective in hereditary hemo-chromatosis, normally is expressed in crypt enterocytes of the duodenum where it has a unique, predominantly intracellular localization. In placenta, the HFE protein co-localizes with and forms a stable association with the transferrin receptor (TfR), providing a link between the HFE protein and iron transport. Immunocytochemistry shows that the HFE protein and TfR both are expressed in the crypt enterocytes. Western blots show that, as is the case in human placenta, the HFE protein in crypt enterocytes is physically associated with the TfR and with ÉÇ2-microglobulin.
Reactivity: Human
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

HFE protein structure - BS6621 shown in red.