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PNPLA6
Patatin like phospholipase domain containing 6iPLA2delta, NTE, SPG39, sws
This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Top validated antibodies |
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| Proteintech Group |  14261-1-AP |
2 references | Polyclonal |
WB
EL
ICC
IP
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| Invitrogen Antibodies | 14261-1-AP |
Polyclonal |
WB
ICC
IP
OA
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| NovoPro Bioscience Inc. | 113982 |
Polyclonal |
WB
EL
ICC
IP
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| Wuhan Fine Biotech Co., Ltd. | FNab06591 |
Polyclonal |
WB
EL
ICC
IP
|
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| Novus Biologicals | H00010908-M08 |
Monoclonal |
WB
EL
IHC
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