Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 16000-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16000-1-AP, RRID:AB_2103936
- Product name
- FGL1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FGL1 antibody (Cat. #16000-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Proteomics identifies a novel role of fibrinogen-like protein 1 in Crohn's disease.
Fibrinogen-Like Protein 1 Modulates Sorafenib Resistance in Human Hepatocellular Carcinoma Cells.
Eicosapentaenoic Acid Inhibits KRAS Mutant Pancreatic Cancer Cell Growth by Suppressing Hepassocin Expression and STAT3 Phosphorylation.
Regulating the immunosuppressive tumor microenvironment to enhance breast cancer immunotherapy using pH-responsive hybrid membrane-coated nanoparticles.
Oxysophocarpine suppresses hepatocellular carcinoma growth and sensitizes the therapeutic blockade of anti-Lag-3 via reducing FGL1 expression.
The co-expression characteristics of LAG3 and PD-1 on the T cells of patients with breast cancer reveal a new therapeutic strategy.
Targeting fibrinogen-like protein 1 is a novel therapeutic strategy to combat obesity.
Role of placental fibrinogen-like protein 1 in gestational diabetes.
Plasma Fibrinogen-Like 1 as a Potential Biomarker for Radiation-Induced Liver Injury.
Unsaturated Fatty Acids Increase the Expression of Hepassocin through a Signal Transducer and Activator of Transcription 3-Dependent Pathway in HepG2 Cells.
A novel hepatokine, HFREP1, plays a crucial role in the development of insulin resistance and type 2 diabetes.
Sun XL, Qiao LC, Gong J, Wen K, Xu ZZ, Yang BL
World journal of gastroenterology 2021 Sep 21;27(35):5946-5957
World journal of gastroenterology 2021 Sep 21;27(35):5946-5957
Fibrinogen-Like Protein 1 Modulates Sorafenib Resistance in Human Hepatocellular Carcinoma Cells.
Son Y, Shin NR, Kim SH, Park SC, Lee HJ
International journal of molecular sciences 2021 May 19;22(10)
International journal of molecular sciences 2021 May 19;22(10)
Eicosapentaenoic Acid Inhibits KRAS Mutant Pancreatic Cancer Cell Growth by Suppressing Hepassocin Expression and STAT3 Phosphorylation.
Chiu CF, Hsu MI, Yeh HY, Park JM, Shen YS, Tung TH, Huang JJ, Wu HT, Huang SY
Biomolecules 2021 Mar 2;11(3)
Biomolecules 2021 Mar 2;11(3)
Regulating the immunosuppressive tumor microenvironment to enhance breast cancer immunotherapy using pH-responsive hybrid membrane-coated nanoparticles.
Gong C, Yu X, Zhang W, Han L, Wang R, Wang Y, Gao S, Yuan Y
Journal of nanobiotechnology 2021 Feb 25;19(1):58
Journal of nanobiotechnology 2021 Feb 25;19(1):58
Oxysophocarpine suppresses hepatocellular carcinoma growth and sensitizes the therapeutic blockade of anti-Lag-3 via reducing FGL1 expression.
Wang J, Wei W, Tang Q, Lu L, Luo Z, Li W, Lu Y, Pu J
Cancer medicine 2020 Oct;9(19):7125-7136
Cancer medicine 2020 Oct;9(19):7125-7136
The co-expression characteristics of LAG3 and PD-1 on the T cells of patients with breast cancer reveal a new therapeutic strategy.
Du H, Yi Z, Wang L, Li Z, Niu B, Ren G
International immunopharmacology 2020 Jan;78:106113
International immunopharmacology 2020 Jan;78:106113
Targeting fibrinogen-like protein 1 is a novel therapeutic strategy to combat obesity.
Wu HT, Chen SC, Fan KC, Kuo CH, Lin SY, Wang SH, Chang CJ, Li HY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2958-2967
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2958-2967
Role of placental fibrinogen-like protein 1 in gestational diabetes.
Kang L, Li HY, Ou HY, Wu P, Wang SH, Chang CJ, Lin SY, Wu CL, Wu HT
Translational research : the journal of laboratory and clinical medicine 2020 Apr;218:73-80
Translational research : the journal of laboratory and clinical medicine 2020 Apr;218:73-80
Plasma Fibrinogen-Like 1 as a Potential Biomarker for Radiation-Induced Liver Injury.
Han NK, Jung MG, Jeong YJ, Son Y, Han SC, Park S, Lim YB, Lee YJ, Kim SH, Park SC, Lee HJ
Cells 2019 Sep 6;8(9)
Cells 2019 Sep 6;8(9)
Unsaturated Fatty Acids Increase the Expression of Hepassocin through a Signal Transducer and Activator of Transcription 3-Dependent Pathway in HepG2 Cells.
Cheng KP, Ou HY, Hung HC, Li CH, Fan KC, Wu JS, Wu HT, Chang CJ
Lipids 2018 Sep;53(9):863-869
Lipids 2018 Sep;53(9):863-869
A novel hepatokine, HFREP1, plays a crucial role in the development of insulin resistance and type 2 diabetes.
Wu HT, Ou HY, Hung HC, Su YC, Lu FH, Wu JS, Yang YC, Wu CL, Chang CJ
Diabetologia 2016 Aug;59(8):1732-42
Diabetologia 2016 Aug;59(8):1732-42
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 16000-1-AP(FGL1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 16000-1-AP(FGL1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FGL1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FGL1. This antibody recognizes human, mouse, rat antigen. The FGL1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.