Tissue expression
Cell line expression
Protein structure
PVR
PVR cell adhesion moleculeCD155, HVED, Necl-5, NECL5, PVS, Tage4
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
11 references | Monoclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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R&D Systems | ![]() |
6 references | Monoclonal |
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Boster Biological Technology | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
6 references | Monoclonal |
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