CABT-B10548

antibody from Creative Diagnostics

Targeting: LATS2

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

CABT-B10548

Provider

Creative Diagnostics

Product name

Mouse anti-Human LATS2 monoclonal antibody, clone TU4C22

Antibody type

Monoclonal

Description

This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

TU4C22

Vial size

50 _g

Storage

Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.