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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [12]
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- Product number
- BML-PW8895-0100 - Provider product page
- Provider
- Enzo Life Sciences
- Product name
- Proteasome 20S _5 subunit (human) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 100 μl
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20¡C.
Submitted references SOD1 deficiency decreases proteasomal function, leading to the accumulation of ubiquitinated proteins in erythrocytes.
Efficacy of panobinostat and marizomib in acute myeloid leukemia and bortezomib-resistant models.
Skeletal muscle myotubes in severe obesity exhibit altered ubiquitin-proteasome and autophagic/lysosomal proteolytic flux.
The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.
The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells.
Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer.
RedOx status, proteasome and APEH: insights into anticancer mechanisms of t10,c12-conjugated linoleic acid isomer on A375 melanoma cells.
Proteasome inhibitors protect the steatotic and non-steatotic liver graft against cold ischemia reperfusion injury.
Negative regulation of 26S proteasome stability via calpain-mediated cleavage of Rpn10 subunit upon mitochondrial dysfunction in neurons.
A putative role for the immunoproteasome in the maintenance of pluripotency in human embryonic stem cells.
Bortezomib resistance in a myeloma cell line is associated to PSMβ5 overexpression and polyploidy.
Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62.
Homma T, Kurahashi T, Lee J, Kang ES, Fujii J
Archives of biochemistry and biophysics 2015 Oct 1;583:65-72
Archives of biochemistry and biophysics 2015 Oct 1;583:65-72
Efficacy of panobinostat and marizomib in acute myeloid leukemia and bortezomib-resistant models.
Corrales-Medina FF, Manton CA, Orlowski RZ, Chandra J
Leukemia research 2015 Mar;39(3):371-9
Leukemia research 2015 Mar;39(3):371-9
Skeletal muscle myotubes in severe obesity exhibit altered ubiquitin-proteasome and autophagic/lysosomal proteolytic flux.
Bollinger LM, Powell JJ, Houmard JA, Witczak CA, Brault JJ
Obesity (Silver Spring, Md.) 2015 Jun;23(6):1185-93
Obesity (Silver Spring, Md.) 2015 Jun;23(6):1185-93
The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.
Sparks A, Dayal S, Das J, Robertson P, Menendez S, Saville MK
Oncogene 2014 Sep 18;33(38):4685-96
Oncogene 2014 Sep 18;33(38):4685-96
The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells.
Hamouda MA, Belhacene N, Puissant A, Colosetti P, Robert G, Jacquel A, Mari B, Auberger P, Luciano F
Oncotarget 2014 Aug 15;5(15):6252-66
Oncotarget 2014 Aug 15;5(15):6252-66
Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer.
Cron KR, Zhu K, Kushwaha DS, Hsieh G, Merzon D, Rameseder J, Chen CC, D'Andrea AD, Kozono D
PloS one 2013;8(9):e73710
PloS one 2013;8(9):e73710
RedOx status, proteasome and APEH: insights into anticancer mechanisms of t10,c12-conjugated linoleic acid isomer on A375 melanoma cells.
Bergamo P, Cocca E, Palumbo R, Gogliettino M, Rossi M, Palmieri G
PloS one 2013;8(11):e80900
PloS one 2013;8(11):e80900
Proteasome inhibitors protect the steatotic and non-steatotic liver graft against cold ischemia reperfusion injury.
Zaouali MA, Bardag-Gorce F, Carbonell T, Oliva J, Pantazi E, Bejaoui M, Ben Abdennebi H, Rimola A, Roselló-Catafau J
Experimental and molecular pathology 2013 Apr;94(2):352-9
Experimental and molecular pathology 2013 Apr;94(2):352-9
Negative regulation of 26S proteasome stability via calpain-mediated cleavage of Rpn10 subunit upon mitochondrial dysfunction in neurons.
Huang Q, Wang H, Perry SW, Figueiredo-Pereira ME
The Journal of biological chemistry 2013 Apr 26;288(17):12161-74
The Journal of biological chemistry 2013 Apr 26;288(17):12161-74
A putative role for the immunoproteasome in the maintenance of pluripotency in human embryonic stem cells.
Atkinson SP, Collin J, Irina N, Anyfantis G, Kyung BK, Lako M, Armstrong L
Stem cells (Dayton, Ohio) 2012 Jul;30(7):1373-84
Stem cells (Dayton, Ohio) 2012 Jul;30(7):1373-84
Bortezomib resistance in a myeloma cell line is associated to PSMβ5 overexpression and polyploidy.
Balsas P, Galán-Malo P, Marzo I, Naval J
Leukemia research 2012 Feb;36(2):212-8
Leukemia research 2012 Feb;36(2):212-8
Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62.
Myeku N, Figueiredo-Pereira ME
The Journal of biological chemistry 2011 Jun 24;286(25):22426-40
The Journal of biological chemistry 2011 Jun 24;286(25):22426-40
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