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- References [8]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN2842102 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-PI3KC3 (AA 24-53), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 24-53, N-Term
- Antibody clone number
- RB1695
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Induction of autophagy is essential for monocyte-macrophage differentiation.
The class III kinase Vps34 promotes T lymphocyte survival through regulating IL-7Rα surface expression.
Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway.
A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1.
Is autophagy rather than apoptosis the regression driver in imatinib-treated gastrointestinal stromal tumors?
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG.
Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade.
A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system.
Zhang Y, Morgan MJ, Chen K, Choksi S, Liu ZG
Blood 2012 Mar 22;119(12):2895-905
Blood 2012 Mar 22;119(12):2895-905
The class III kinase Vps34 promotes T lymphocyte survival through regulating IL-7Rα surface expression.
McLeod IX, Zhou X, Li QJ, Wang F, He YW
Journal of immunology (Baltimore, Md. : 1950) 2011 Nov 15;187(10):5051-61
Journal of immunology (Baltimore, Md. : 1950) 2011 Nov 15;187(10):5051-61
Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway.
Zhou X, Wang L, Hasegawa H, Amin P, Han BX, Kaneko S, He Y, Wang F
Proceedings of the National Academy of Sciences of the United States of America 2010 May 18;107(20):9424-9
Proceedings of the National Academy of Sciences of the United States of America 2010 May 18;107(20):9424-9
A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1.
Wang J, Whiteman MW, Lian H, Wang G, Singh A, Huang D, Denmark T
The Journal of biological chemistry 2009 Aug 7;284(32):21412-24
The Journal of biological chemistry 2009 Aug 7;284(32):21412-24
Is autophagy rather than apoptosis the regression driver in imatinib-treated gastrointestinal stromal tumors?
Miselli F, Negri T, Gronchi A, Losa M, Conca E, Brich S, Fumagalli E, Fiore M, Casali PG, Pierotti MA, Tamborini E, Pilotti S
Translational oncology 2008 Dec;1(4):177-86
Translational oncology 2008 Dec;1(4):177-86
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG.
Liang C, Feng P, Ku B, Dotan I, Canaani D, Oh BH, Jung JU
Nature cell biology 2006 Jul;8(7):688-99
Nature cell biology 2006 Jul;8(7):688-99
Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade.
Vergne I, Chua J, Deretic V
The Journal of experimental medicine 2003 Aug 18;198(4):653-9
The Journal of experimental medicine 2003 Aug 18;198(4):653-9
A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system.
Volinia S, Dhand R, Vanhaesebroeck B, MacDougall LK, Stein R, Zvelebil MJ, Domin J, Panaretou C, Waterfield MD
The EMBO journal 1995 Jul 17;14(14):3339-48
The EMBO journal 1995 Jul 17;14(14):3339-48
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
