FNab04143

antibody from FineTest Biotech

Targeting: IFITM2 1-8D, DSPA2c

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Validation data

Product number: FNab04143 - Provider product page
Provider: FineTest Biotech
Product name: IFITM2-specific antibody
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus(SARS-CoV), Marburg virus(MARV), Ebola virus(EBOV), Dengue virus(DNV), West Nile virus(WNV), human immunodeficiency virus type 1(HIV-1) and vesicular stomatitis virus(VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: interferon induced transmembrane pr otein 2
Epitope: IgG1
Isotype: IgG
Antibody clone number: 9C2
Vial size: 100¦Ìg
Concentration: Protein A+G purification
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

IFITM2 protein structure - FNab04143 shown in red.