NBP2-29465

antibody from Novus Biologicals

Targeting: CD74 DHLAG

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Antibody data

Submit

Validation data

Product number: NBP2-29465 - Provider product page
Provider: Novus Biologicals
Product name: Mouse Monoclonal CD74 Antibody
Antibody type: Monoclonal
Description: Protein G purified. It recognizes a protein of ~35kDa, identified as CD74 (Workshop IV). CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+). This antibody can be used for the identification of B cell lymphoma and leukemias. It also stains activated neoplastic cells in T cell lymphomas and Sternberg-reed cells.
Reactivity: Human, Mouse, Rat
Host: Mouse
Isotype: IgG
Vial size: 0.1 mg
Concentration: 0.2 mg/ml
Storage: Store at 4C.

CD74 protein structure - NBP2-29465 shown in red.