Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Other assay [1]
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Validation data
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- Product number
- PA5-25258 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- DHRS2 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 400 µL
- Concentration
- 0.5 mg/mL
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references DHRS2 mediates cell growth inhibition induced by Trichothecin in nasopharyngeal carcinoma.
DHRS2 inhibits cell growth and motility in esophageal squamous cell carcinoma.
Luo X, Li N, Zhao X, Liao C, Ye R, Cheng C, Xu Z, Quan J, Liu J, Cao Y
Journal of experimental & clinical cancer research : CR 2019 Jul 10;38(1):300
Journal of experimental & clinical cancer research : CR 2019 Jul 10;38(1):300
DHRS2 inhibits cell growth and motility in esophageal squamous cell carcinoma.
Zhou Y, Wang L, Ban X, Zeng T, Zhu Y, Li M, Guan XY, Li Y
Oncogene 2018 Feb 22;37(8):1086-1094
Oncogene 2018 Feb 22;37(8):1086-1094
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis using a DHRS2 polyclonal antibody (Product # PA5-25258) in MCF-7 cell lysates (35 µg per lane).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis in formalin-fixed, paraffin-embedded human skin carcinoma using a DHRS2 polyclonal antibody (Product # PA5-25258), followed by HRP-conjugated secondary antibody and DAB staining.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 1 DHRS2 downregulation was significantly associated with poorer prognosis of ESCC. ( a ) The representative pictures of DHRS2 staining in ESCC tumor tissue and paired non-tumor tissue. The boxed regions were magnified and shown in the right panels. ( b ) Kaplan-Meier analysis showed that DHRS2 downregulation was significantly associated with ESCC patients' poorer survival. ( c ) The relative quantification of DHRS2-V1 and DHRS2-V2 in ESCC cell lines, NE1 (an immortalized human esophageal epithelial cell line) and non-tumor esophageal tissues pool (three cases).