BS7889

antibody from Bioworld Technology, Inc
Targeting: ING4 my036, p29ING4
Provider product page for BS7889
Western blot
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
BS7889 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ING4 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human ING4.
Description
Inhibitor of growth protein (ING) family of nuclear proteins, also designated ING tumor suppressor proteins, inhibit tumor progression by modulating the transcriptional outputs of signaling pathways, which in turn regulates cell proliferation. Members of this family include ING1, ING2, ING3, ING4 and INGX. ING4 localizes to the nucleus and may inhibit tumor progression by adjusting the transcriptional output of signaling pathways which regulate cell proliferation. When complexed with RELA, ING4 can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes. ING4 interacts with HIF prolyl hydroxylase 2 (EGLN1), which represses the activity of hypoxia inducible factor (HIF).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ING4 protein structure - BS7889 shown in red.