BS7485

antibody from Bioworld Technology, Inc
Targeting: PIWIL2 CT80, FLJ10351, HILI, Mili
Provider product page for BS7485
Western blot
Immunohistochemistry

Antibody data

Product number
BS7485 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PIWIL2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PIWIL2.
Description
PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells. Its presence in oocytes suggests that it may participate in similar functions during oogenesis in females. Indirectly modulate expression of genes such as PDGFRB, SLC2A1, ITGA6, GJA7, THY1, CD9 and STRA8. Inhibits tumor cell growth when repressed. When overexpressed, acts as an oncogene by inhibition of apoptosis and promotion of proliferation in tumors.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PIWIL2 protein structure - BS7485 shown in red.