Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APG01188G - Provider product page
- Provider
- Leading Biology
- Product name
- CIRP / CIRBP Antibody (aa161-172)
- Antibody type
- Polyclonal
- Description
- Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold- induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.
- Reactivity
- Human, Mouse, Rat, Canine, Hamster, Porcine, Simian
- Host
- Goat
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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