BS60455

antibody from Bioworld Technology, Inc
Targeting: WFS1 DFNA14, DFNA38, DFNA6, DIDMOAD, WFS
Provider product page for BS60455

Antibody data

Product number
BS60455 - Provider product page
Provider
Bioworld Technology, Inc
Product name
WFS1 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human WFS1.
Description
The Wolframin gene encodes a protein found in endoplasmic reticulum membrane of several tissues including brain, pancreas, lung and placenta. Loss-of-function mutations in both alleles result in Wolfram syndrome (also known as DIDMOAD, an autosomal recessive disorder that causes juvenile diabetes mellitus, diabetes insipidus, optic atrophy and a number of neurological symptoms including deafness, ataxia and peripheral neuropathy. A large number and variety of mutations in this gene, particularly in exon 8, can be associated with Wolfram syndrome. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
WFS1 protein structure - BS60455 shown in red.