Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 15376-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15376-1-AP, RRID:AB_2286678
- Product name
- SPTLC1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SPTLC1 antibody (Cat. #15376-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty.
Activation of Mitochondrial Unfolded Protein Response in SHSY5Y Expressing APP Cells and APP/PS1 Mice.
Knockout of neutrophil elastase protects against western diet induced nonalcoholic steatohepatitis in mice by regulating hepatic ceramides metabolism.
Inhibition of serine palmitoyltransferase reduces Aβ and tau hyperphosphorylation in a murine model: a safe therapeutic strategy for Alzheimer's disease.
MicroRNA-137/181c regulates serine palmitoyltransferase and in turn amyloid β, novel targets in sporadic Alzheimer's disease.
Heras V, Castellano JM, Fernandois D, Velasco I, Rodríguez-Vazquez E, Roa J, Vazquez MJ, Ruiz-Pino F, Rubio M, Pineda R, Torres E, Avendaño MS, Paredes A, Pinilla L, Belsham D, Diéguez C, Gaytán F, Casals N, López M, Tena-Sempere M
Cell metabolism 2020 Dec 1;32(6):951-966.e8
Cell metabolism 2020 Dec 1;32(6):951-966.e8
Activation of Mitochondrial Unfolded Protein Response in SHSY5Y Expressing APP Cells and APP/PS1 Mice.
Shen Y, Ding M, Xie Z, Liu X, Yang H, Jin S, Xu S, Zhu Z, Wang Y, Wang D, Xu L, Zhou X, Wang P, Bi J
Frontiers in cellular neuroscience 2019;13:568
Frontiers in cellular neuroscience 2019;13:568
Knockout of neutrophil elastase protects against western diet induced nonalcoholic steatohepatitis in mice by regulating hepatic ceramides metabolism.
Chen J, Liang B, Bian D, Luo Y, Yang J, Li Z, Zhuang Z, Zang S, Shi J
Biochemical and biophysical research communications 2019 Oct 22;518(4):691-697
Biochemical and biophysical research communications 2019 Oct 22;518(4):691-697
Inhibition of serine palmitoyltransferase reduces Aβ and tau hyperphosphorylation in a murine model: a safe therapeutic strategy for Alzheimer's disease.
Geekiyanage H, Upadhye A, Chan C
Neurobiology of aging 2013 Aug;34(8):2037-51
Neurobiology of aging 2013 Aug;34(8):2037-51
MicroRNA-137/181c regulates serine palmitoyltransferase and in turn amyloid β, novel targets in sporadic Alzheimer's disease.
Geekiyanage H, Chan C
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Oct 12;31(41):14820-30
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Oct 12;31(41):14820-30
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 15376-1-AP(SPTLC1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 15376-1-AP(SPTLC1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SPTLC1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SPTLC1. This antibody recognizes human, mouse, rat antigen. The SPTLC1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.