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- Product number
- ABIN396576 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 675-774) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 675-774
- Isotype
- IgG
- Antibody clone number
- 5D2
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Functional analysis of LOXL2 in pancreatic carcinoma.
Modulation of lysyl oxidase-like 2 enzymatic activity by an allosteric antibody inhibitor.
Forkhead box A1 transcriptional pathway in KRT7-expressing esophageal squamous cell carcinomas with extensive lymph node metastasis.
The lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in hypoxia: insights into cellular transformation processes mediated by HIF-1.
Differential expression of the LOX family genes in human colorectal adenocarcinomas.
Rückert F, Joensson P, Saeger HD, Grützmann R, Pilarsky C
International journal of colorectal disease 2010 Mar;25(3):303-11
International journal of colorectal disease 2010 Mar;25(3):303-11
Modulation of lysyl oxidase-like 2 enzymatic activity by an allosteric antibody inhibitor.
Rodriguez HM, Vaysberg M, Mikels A, McCauley S, Velayo AC, Garcia C, Smith V
The Journal of biological chemistry 2010 Jul 2;285(27):20964-74
The Journal of biological chemistry 2010 Jul 2;285(27):20964-74
Forkhead box A1 transcriptional pathway in KRT7-expressing esophageal squamous cell carcinomas with extensive lymph node metastasis.
Sano M, Aoyagi K, Takahashi H, Kawamura T, Mabuchi T, Igaki H, Tachimori Y, Kato H, Ochiai A, Honda H, Nimura Y, Nagino M, Yoshida T, Sasaki H
International journal of oncology 2010 Feb;36(2):321-30
International journal of oncology 2010 Feb;36(2):321-30
The lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in hypoxia: insights into cellular transformation processes mediated by HIF-1.
Schietke R, Warnecke C, Wacker I, Schödel J, Mole DR, Campean V, Amann K, Goppelt-Struebe M, Behrens J, Eckardt KU, Wiesener MS
The Journal of biological chemistry 2010 Feb 26;285(9):6658-69
The Journal of biological chemistry 2010 Feb 26;285(9):6658-69
Differential expression of the LOX family genes in human colorectal adenocarcinomas.
Kim Y, Roh S, Park JY, Kim Y, Cho DH, Kim JC
Oncology reports 2009 Oct;22(4):799-804
Oncology reports 2009 Oct;22(4):799-804
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA
