CABT-BL1147

antibody from Creative Diagnostics

Targeting: CPZ

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-BL1147

Provider

Creative Diagnostics

Product name

Anti-CPZ polyclonal antibody

Antibody type

Polyclonal

Description

Chlorpromazine (as chlorpromazine hydrochloride, abbreviated CPZ) is a typical antipsychotic. Chlorpromazine works on a variety of receptors in the central nervous system, producing anticholinergic, antidopaminergic, antihistaminic, and weak antiadrenergic effects. Both the clinical indications and side effect profile of CPZ are determined by this broad action: its anticholinergic properties cause constipation, sedation, and hypotension, and help relieve nausea. It also has anxiolytic (anxiety-relieving) properties. Its antidopaminergic properties can cause extrapyramidal symptoms such as akathisia (restlessness, aka the 'largactil shuffle' where the patient walks almost constantly, despite having nowhere to go due to mandatory confinement, and takes small, shuffling steps) and dystonia. It is known to cause tardive dyskinesia, which can be irreversible.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Storage

Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.