abx028904

antibody from Abbexa

Targeting: DPH1 DPH2L, DPH2L1, OVCA1

No application information provided.

Antibody Data

Product number

abx028904

Provider

Abbexa

Product name

2-(3-Amino-3-Carboxypropyl)histidine Synthase Subunit 1 (DPH1) Antibody

Antibody type

Polyclonal

Description

Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM].

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

80 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.