Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 15235-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15235-1-AP, RRID:AB_2254794
- Product name
- SLC25A1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SLC25A1 antibody (Cat. #15235-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SLC25A1 promotes tumor growth and survival by reprogramming energy metabolism in colorectal cancer.
Regulation on Citrate Influx and Metabolism through Inhibiting SLC13A5 and ACLY: A Novel Mechanism Mediating the Therapeutic Effects of Curcumin on NAFLD.
Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH.
Long non-coding RNA BRM promotes proliferation and invasion of papillary thyroid carcinoma by regulating the microRNA-331-3p/SLC25A1 axis.
Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress.
A novel isoform of myosin 18A (Myo18Aγ) is an essential sarcomeric protein in mouse heart.
Glycolytic Switch Is Required for Transdifferentiation to Endothelial Lineage.
An overview of combined D-2- and L-2-hydroxyglutaric aciduria: functional analysis of CIC variants.
Deficiency in SLC25A1, encoding the mitochondrial citrate carrier, causes combined D-2- and L-2-hydroxyglutaric aciduria.
Yang Y, He J, Zhang B, Zhang Z, Jia G, Liu S, Wu T, He X, Wang N
Cell death & disease 2021 Nov 27;12(12):1108
Cell death & disease 2021 Nov 27;12(12):1108
Regulation on Citrate Influx and Metabolism through Inhibiting SLC13A5 and ACLY: A Novel Mechanism Mediating the Therapeutic Effects of Curcumin on NAFLD.
Sun Q, Niu Q, Guo Y, Zhuang Y, Li X, Liu J, Li N, Li Z, Huang F, Qiu Z
Journal of agricultural and food chemistry 2021 Aug 11;69(31):8714-8725
Journal of agricultural and food chemistry 2021 Aug 11;69(31):8714-8725
Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH.
Tan M, Mosaoa R, Graham GT, Kasprzyk-Pawelec A, Gadre S, Parasido E, Catalina-Rodriguez O, Foley P, Giaccone G, Cheema A, Kallakury B, Albanese C, Yi C, Avantaggiati ML
Cell death and differentiation 2020 Jul;27(7):2143-2157
Cell death and differentiation 2020 Jul;27(7):2143-2157
Long non-coding RNA BRM promotes proliferation and invasion of papillary thyroid carcinoma by regulating the microRNA-331-3p/SLC25A1 axis.
Liu S, Zhang D, Chen L, Gao S, Huang X
Oncology letters 2020 Apr;19(4):3071-3078
Oncology letters 2020 Apr;19(4):3071-3078
Proline biosynthesis is a vent for TGFβ-induced mitochondrial redox stress.
Schwörer S, Berisa M, Violante S, Qin W, Zhu J, Hendrickson RC, Cross JR, Thompson CB
The EMBO journal 2020 Apr 15;39(8):e103334
The EMBO journal 2020 Apr 15;39(8):e103334
A novel isoform of myosin 18A (Myo18Aγ) is an essential sarcomeric protein in mouse heart.
Horsthemke M, Nutter LMJ, Bachg AC, Skryabin BV, Honnert U, Zobel T, Bogdan S, Stoll M, Seidl MD, Müller FU, Ravens U, Unger A, Linke WA, van Gorp PRR, de Vries AAF, Bähler M, Hanley PJ
The Journal of biological chemistry 2019 May 3;294(18):7202-7218
The Journal of biological chemistry 2019 May 3;294(18):7202-7218
Glycolytic Switch Is Required for Transdifferentiation to Endothelial Lineage.
Lai L, Reineke E, Hamilton DJ, Cooke JP
Circulation 2019 Jan 2;139(1):119-133
Circulation 2019 Jan 2;139(1):119-133
An overview of combined D-2- and L-2-hydroxyglutaric aciduria: functional analysis of CIC variants.
Pop A, Williams M, Struys EA, Monné M, Jansen EEW, De Grassi A, Kanhai WA, Scarcia P, Ojeda MRF, Porcelli V, van Dooren SJM, Lennertz P, Nota B, Abdenur JE, Coman D, Das AM, El-Gharbawy A, Nuoffer JM, Polic B, Santer R, Weinhold N, Zuccarelli B, Palmieri F, Palmieri L, Salomons GS
Journal of inherited metabolic disease 2018 Mar;41(2):169-180
Journal of inherited metabolic disease 2018 Mar;41(2):169-180
Deficiency in SLC25A1, encoding the mitochondrial citrate carrier, causes combined D-2- and L-2-hydroxyglutaric aciduria.
Nota B, Struys EA, Pop A, Jansen EE, Fernandez Ojeda MR, Kanhai WA, Kranendijk M, van Dooren SJ, Bevova MR, Sistermans EA, Nieuwint AW, Barth M, Ben-Omran T, Hoffmann GF, de Lonlay P, McDonald MT, Meberg A, Muntau AC, Nuoffer JM, Parini R, Read MH, Renneberg A, Santer R, Strahleck T, van Schaftingen E, van der Knaap MS, Jakobs C, Salomons GS
American journal of human genetics 2013 Apr 4;92(4):627-31
American journal of human genetics 2013 Apr 4;92(4):627-31
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 15235-1-AP(SLC25A1 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 15235-1-AP(SLC25A1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SLC25A1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SLC25A1. This antibody recognizes human, mouse, rat antigen. The SLC25A1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.