Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11-8086 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-AP3 Delta Antibody
- Antibody type
- Polyclonal
- Description
- AP3D1 (AP-3 complex subunit delta-1) encodes the delta 1 subunit of an adaptor protein regulating intracellular vesicle-mediated transport (19631730). Lack of expression of functional AP-3, leads to a deficiency in vesicle transport and storage, which affects neurotransmitter vesicle turnover and release in the central nervous system (19032734). The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and directly involved in trafficking to lysosomes. It is implicated in intracellular biogenesis and trafficking of pigment granules and possibly platelet dense granules and neurotransmitter vesicles.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant AP3 De
lta protein (amino acids 400-680) w
as used as the immunogen for this a
ntibody.- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
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- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of AP3 Delta. Anti-AP3 Delta antibody (11-8086) was used at 4 µg/ml on 293 lysate.