NUP155

Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. [provided by RefSeq, May 2013]

Description

Nucleoporin 155

Tissue specificity

Tissue enriched (testis)

Subcell location

Nuclear membrane

Predicted location

Intracellular

Protein family

Disease related genes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transporters

Chromosome

5 (37288137 - 37371106)

Ensembl ID

ENSG00000113569  (ver. 103.38)

Orthologs

Mouse Nup155: ENSMUSG00000022142

UniProt

O75694

neXtProt

NX_O75694

Human splice variants
Mouse splice variants

Protein structure