ABIN152043

antibody from antibodies-online

Targeting: RICTOR AVO3, KIAA1999, MGC39830, PIA

Provider product page for ABIN152043

Western blot

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [18]
Comments [0]
Validations
Western blot [4]
Immunocytochemistry [1]
Immunohistochemistry [1]
Flow cytometry [1]

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Product number: ABIN152043 - Provider product page
Provider: antibodies-online
Product name: anti-RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) (C-Term) antibody
Antibody type: Polyclonal
Description: Immunogen affinity purified
Reactivity: Human, Mouse
Host: Rabbit
Epitope: C-Term
Vial size: 100 μL
Storage: Store at 4°C. Do not freeze.
Handling: Do not freeze.

RICTOR protein structure - ABIN152043 shown in red.

Submitted references Uncoupling TORC2 from AGC kinases inhibits tumour growth.

Cameron AJM, Veeriah S, Marshall JJT, Murray ER, Larijani B, Parker PJ
Oncotarget 2017 Oct 17;8(49):84685-84696

Cadmium Activates Multiple Signaling Pathways That Coordinately Stimulate Akt Activity to Enhance c-Myc mRNA Stability.

Tsai JS, Chao CH, Lin LY
PloS one 2016;11(1):e0147011

Pegylated IFN-α suppresses hepatitis C virus by promoting the DAPK-mTOR pathway.

Liu WL, Yang HC, Hsu CS, Wang CC, Wang TS, Kao JH, Chen DS
Proceedings of the National Academy of Sciences of the United States of America 2016 Dec 20;113(51):14799-14804

17ß-Estradiol regulates mTORC2 sensitivity to rapamycin in adaptive cardiac remodeling.

Kusch A, Schmidt M, Gürgen D, Postpieszala D, Catar R, Hegner B, Davidson MM, Mahmoodzadeh S, Dragun D
PloS one 2015;10(4):e0123385

Rictor negatively regulates high-affinity receptors for IgE-induced mast cell degranulation.

Smrz D, Cruse G, Beaven MA, Kirshenbaum A, Metcalfe DD, Gilfillan AM
Journal of immunology (Baltimore, Md. : 1950) 2014 Dec 15;193(12):5924-32

Novel mTOR inhibitory activity of ciclopirox enhances parthenolide antileukemia activity.

Sen S, Hassane DC, Corbett C, Becker MW, Jordan CT, Guzman ML
Experimental hematology 2013 Sep;41(9):799-807.e4

PI3K regulation of the SKP-2/p27 axis through mTORC2.

Shanmugasundaram K, Block K, Nayak BK, Livi CB, Venkatachalam MA, Sudarshan S
Oncogene 2013 Apr 18;32(16):2027-36

HLA class I-mediated stress fiber formation requires ERK1/2 activation in the absence of an increase in intracellular Ca2+ in human aortic endothelial cells.

Ziegler ME, Jin YP, Young SH, Rozengurt E, Reed EF
American journal of physiology. Cell physiology 2012 Oct 15;303(8):C872-82

mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.

Gulhati P, Bowen KA, Liu J, Stevens PD, Rychahou PG, Chen M, Lee EY, Weiss HL, O'Connor KL, Gao T, Evers BM
Cancer research 2011 May 1;71(9):3246-56

Contribution of human amniotic fluid stem cells to renal tissue formation depends on mTOR.

Siegel N, Rosner M, Unbekandt M, Fuchs C, Slabina N, Dolznig H, Davies JA, Lubec G, Hengstschläger M
Human molecular genetics 2010 Sep 1;19(17):3320-31

Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer.

Gulhati P, Cai Q, Li J, Liu J, Rychahou PG, Qiu S, Lee EY, Silva SR, Bowen KA, Gao T, Evers BM
Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Dec 1;15(23):7207-16

Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival.

McDonald PC, Oloumi A, Mills J, Dobreva I, Maidan M, Gray V, Wederell ED, Bally MB, Foster LJ, Dedhar S
Cancer research 2008 Mar 15;68(6):1618-24

A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes.

Hagan GN, Lin Y, Magnuson MA, Avruch J, Czech MP
Molecular and cellular biology 2008 Jul;28(13):4215-26

HLA class I antibody-mediated endothelial cell proliferation via the mTOR pathway.

Jindra PT, Jin YP, Rozengurt E, Reed EF
Journal of immunology (Baltimore, Md. : 1950) 2008 Feb 15;180(4):2357-66

mTORC1 promotes survival through translational control of Mcl-1.

Mills JR, Hippo Y, Robert F, Chen SM, Malina A, Lin CJ, Trojahn U, Wendel HG, Charest A, Bronson RT, Kogan SC, Nadon R, Housman DE, Lowe SW, Pelletier J
Proceedings of the National Academy of Sciences of the United States of America 2008 Aug 5;105(31):10853-8

Rapamycin limits formation of active eukaryotic initiation factor 4F complex following meal feeding in rat hearts.

Vary TC, Deiter G, Lynch CJ
The Journal of nutrition 2007 Aug;137(8):1857-62

Nutrient-dependent multimerization of the mammalian target of rapamycin through the N-terminal HEAT repeat region.

Takahara T, Hara K, Yonezawa K, Sorimachi H, Maeda T
The Journal of biological chemistry 2006 Sep 29;281(39):28605-14

Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity.

Yang Q, Inoki K, Ikenoue T, Guan KL
Genes & development 2006 Oct 15;20(20):2820-32

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