H00001497-M09

antibody from Novus Biologicals

Targeting: CTNS CTNS-LSB, PQLC4, SLC66A4

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Antibody Data

Product number

H00001497-M09

Provider

Novus Biologicals

Proper citation

Novus Cat#H00001497-M09, RRID:AB_538065

Product name

Mouse Monoclonal CTNS Antibody

Antibody type

Monoclonal

Description

IgG purified. CTNS - cystinosis, nephropathic

Reactivity

Human, Mouse, Rat

Host

Mouse

Isotype

IgG

Vial size

0.1 mg

Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

References

Submitted references

The aminoglycoside geneticin permits translational readthrough of the CTNS W138X nonsense mutation in fibroblasts from patients with nephropathic cystinosis.

Brasell EJ, Chu L, El Kares R, Seo JH, Loesch R, Iglesias DM, Goodyer P
Pediatric nephrology (Berlin, Germany) 2019 May;34(5):873-881

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Cystine accumulation attenuates insulin release from the pancreatic β-cell due to elevated oxidative stress and decreased ATP levels.

McEvoy B, Sumayao R, Slattery C, McMorrow T, Newsholme P
The Journal of physiology 2015 Dec 1;593(23):5167-82

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Modulation of CTNS gene expression by intracellular thiols.

Bellomo F, Corallini S, Pastore A, Palma A, Laurenzi C, Emma F, Taranta A
Free radical biology & medicine 2010 Apr 1;48(7):865-72

Western blot

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Western Blot: CTNS Antibody (5G6) [H00001497-M09] - Analysis of CTNS expression in HepG2.

ELISA

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

ELISA: CTNS Antibody (5G6) [H00001497-M09] - Detection limit for recombinant GST tagged CTNS is approximately 0.3ng/ml as a capture antibody.