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- References [7]
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- Product number
- ABIN400818 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mesothelin (MSLN) (Extracellular Domain) antibody
- Antibody type
- Monoclonal
- Antigen
- Recombinant protein corresponding to the extracellular domain of Human Mesothelin
- Description
- Protein A Chromatography.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- Extracellular Domain
- Antibody clone number
- MN-1
- Vial size
- 25 μL
- Concentration
- 1.0 mg/mL (by UV absorbance at 280 nm)
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C or below forlonger. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf life: one year from despatch.
Submitted references Mesothelin expression in human lung cancer.
New monoclonal antibodies to mesothelin useful for immunohistochemistry, fluorescence-activated cell sorting, Western blotting, and ELISA.
Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion.
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE).
Mesothelin is not required for normal mouse development or reproduction.
Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers.
Isolation and characterization of a monoclonal antibody, K1, reactive with ovarian cancers and normal mesothelium.
Ho M, Bera TK, Willingham MC, Onda M, Hassan R, FitzGerald D, Pastan I
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Mar 1;13(5):1571-5
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Mar 1;13(5):1571-5
New monoclonal antibodies to mesothelin useful for immunohistochemistry, fluorescence-activated cell sorting, Western blotting, and ELISA.
Onda M, Willingham M, Nagata S, Bera TK, Beers R, Ho M, Hassan R, Kreitman RJ, Pastan I
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Aug 15;11(16):5840-6
Clinical cancer research : an official journal of the American Association for Cancer Research 2005 Aug 15;11(16):5840-6
Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion.
Rump A, Morikawa Y, Tanaka M, Minami S, Umesaki N, Takeuchi M, Miyajima A
The Journal of biological chemistry 2004 Mar 5;279(10):9190-8
The Journal of biological chemistry 2004 Mar 5;279(10):9190-8
Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE).
Argani P, Iacobuzio-Donahue C, Ryu B, Rosty C, Goggins M, Wilentz RE, Murugesan SR, Leach SD, Jaffee E, Yeo CJ, Cameron JL, Kern SE, Hruban RH
Clinical cancer research : an official journal of the American Association for Cancer Research 2001 Dec;7(12):3862-8
Clinical cancer research : an official journal of the American Association for Cancer Research 2001 Dec;7(12):3862-8
Mesothelin is not required for normal mouse development or reproduction.
Bera TK, Pastan I
Molecular and cellular biology 2000 Apr;20(8):2902-6
Molecular and cellular biology 2000 Apr;20(8):2902-6
Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers.
Chang K, Pastan I
Proceedings of the National Academy of Sciences of the United States of America 1996 Jan 9;93(1):136-40
Proceedings of the National Academy of Sciences of the United States of America 1996 Jan 9;93(1):136-40
Isolation and characterization of a monoclonal antibody, K1, reactive with ovarian cancers and normal mesothelium.
Chang K, Pastan I, Willingham MC
International journal of cancer. Journal international du cancer 1992 Feb 1;50(3):373-81
International journal of cancer. Journal international du cancer 1992 Feb 1;50(3):373-81
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- Image(s): Western Blotting
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Image(s): Immunohistochemistry
