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- References [3]
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- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- ABIN951556 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Chloride Channel, Voltage-Sensitive 7 (CLCN7) (C-Term), (AA 699-728) antibody
- Antibody type
- Polyclonal
- Antigen
- KLH conjugated synthetic peptide between 699-728 amino acids from the C-terminal region of human CLCN7
- Description
- Affinity chromatography on Protein A
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term,AA 699-728
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Osteopetrosis due to homozygous chloride channel ClCN7 mutation mimicking metabolic disease with haematological and neurological impairment.
Novel mutations in Indian patients with autosomal recessive infantile malignant osteopetrosis.
A single-center experience in 20 patients with infantile malignant osteopetrosis.
Furthner D, Biebl A, Weinzettel R, Schmitt K, Lahr G, Ebetsberger G, Rittinger O, Schulz AS
Klinische Padiatrie 2010 May;222(3):180-3
Klinische Padiatrie 2010 May;222(3):180-3
Novel mutations in Indian patients with autosomal recessive infantile malignant osteopetrosis.
Phadke SR, Fischer B, Gupta N, Ranganath P, Kabra M, Kornak U
The Indian journal of medical research 2010 Apr;131:508-14
The Indian journal of medical research 2010 Apr;131:508-14
A single-center experience in 20 patients with infantile malignant osteopetrosis.
Mazzolari E, Forino C, Razza A, Porta F, Villa A, Notarangelo LD
American journal of hematology 2009 Aug;84(8):473-9
American journal of hematology 2009 Aug;84(8):473-9
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- CLCN7 Antibody (C-term) (Cat. #AP50940PU-N) western blot analysis in CEM cell line lysates (35μg/lane).This demonstrates the CLCN7 antibody detected the CLCN7 protein (arrow).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Confocal immunofluorescent analysis of CLCN7 Antibody (C-term)(Cat#AP50940PU-N) with WiDr cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- CLCN7 Antibody (C-term) (Cat. #AP50940PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CLCN7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
