Tissue expression
Cell line expression
Protein structure
SIRPB1
Signal regulatory protein beta 1CD172b, SIRP-BETA-1
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
Top validated antibodies |
|||||
Proteintech Group | ![]() |
2 references | Polyclonal |
|
|
Invitrogen Antibodies | ![]() |
Polyclonal |
|
||
Cusabio Biotech Co., Ltd | ![]() |
Polyclonal |
|
||
Biorbyt | ![]() |
Polyclonal |
|
||
LSBio | ![]() |
Polyclonal |
|