CABT-BL7463

antibody from Creative Diagnostics

Targeting: ENG CD105, END, HHT1, ORW, ORW1

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-BL7463

Provider

Creative Diagnostics

Product name

Anti-ENG Monoclonal antibody, clone NK8/29

Antibody type

Monoclonal

Description

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.

Reactivity

Mouse

Host

Rat

Conjugate

Unconjugated

Isotype

IgG